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What are the serious side effects of taking an excess of the Paracetamol? Overdose of Paracetamole may cause severe life-threatening liver injury. dosis amoxsan 500 mg Taking more than the prescribed dose may also cause kidney injury, decreased platelet count, and even coma. channa 500 mg obat apa Early symptoms of an overdose include nausea, vomiting, and general tiredness